2. Protein Tyrosine Kinase/RTK
  3. FLT3
  4. FLT3-IN-25

FLT3-IN-25 (compound 17) is a potent inhibitor of FLT3, with IC50s of 1.2 nM, 1.4 nM and 1.1 nM for FLT3-WT, FLT3-D835Y and FLT3-ITD, respectively. FLT3-IN-25 plays an important role in acute myeloid leukemia (AML).

For research use only. We do not sell to patients.

FLT3-IN-25 Chemical Structure

FLT3-IN-25 Chemical Structure

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FLT3-IN-25 Related Antibodies

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Description

FLT3-IN-25 (compound 17) is a potent inhibitor of FLT3, with IC50s of 1.2 nM, 1.4 nM and 1.1 nM for FLT3-WT, FLT3-D835Y and FLT3-ITD, respectively. FLT3-IN-25 plays an important role in acute myeloid leukemia (AML)[1].

Molecular Weight

374.44

Formula

C21H22N6O
SMILES

C[C@H]1O[C@@H](C)CN(C2=NN3C(C=C2)=NC=C3C4=CC=C(C5=CNN=C5)C=C4)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FLT3-IN-25 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FLT3-IN-25FLT3Cluster of differentiation antigen 135CD135Fms like tyrosine kinase 3acute myeloid leukemiachronic paincancerInhibitorinhibitorinhibit

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FLT3-IN-25
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HY-162032
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