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Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC50 of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings.

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Fluopipamine Chemical Structure

Fluopipamine Chemical Structure

CAS No. : 885902-66-9

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Description

Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC50 of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings[1].

In Vitro

Fluopipamine (20-100 μM) causes aberrant phenotype in Arabidopsis, such as short root, ectopic lignification and etiolation inhibition[1].
Fluopipamine (20 μM) reduces the incorporation of radiolabeled glucose into cellulose cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

423.49

Formula

C22H26FN7O

CAS No.
SMILES

FC1=C(N2CCN(CC2)CC3=NC(NC4=CC(C)=CC=C4OC)=NC(N)=N3)C=CC=C1

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References
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Fluopipamine Related Classifications

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Product Name:
Fluopipamine
Cat. No.:
HY-163279
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