2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Fmoc-Gly-Gly-D-Phe-OH

Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).

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Fmoc-Gly-Gly-D-Phe-OH Chemical Structure

Fmoc-Gly-Gly-D-Phe-OH Chemical Structure

CAS No. : 2982232-04-0

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Fmoc-Gly-Gly-D-Phe-OH Related Antibodies

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Description

Fmoc-Gly-Gly-D-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Gly-Gly-D-Phe-OH is the D-isomer of Fmoc-Gly-Gly-Phe-OH (HY-131833).

IC50 & Target

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-Gly-Gly-D-Phe-OH Related Antibodies
Molecular Weight

501.53

Formula

C28H27N3O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC(NCC(N[C@H](CC1=CC=CC=C1)C(O)=O)=O)=O)OCC2C3=C(C4=C2C=CC=C4)C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
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Fmoc-Gly-Gly-D-Phe-OH Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-Gly-Gly-D-Phe-OH2982232-04-0ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
Fmoc-Gly-Gly-D-Phe-OH
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HY-131833A
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