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  3. Amino Acid Derivatives
  4. Fmoc-Oic-OH

Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg10]HOE 140, which has bradykinin B1 antagonist activity.

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Fmoc-Oic-OH Chemical Structure

Fmoc-Oic-OH Chemical Structure

CAS No. : 130309-37-4

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Based on 1 publication(s) in Google Scholar

Fmoc-Oic-OH Related Antibodies

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Description

Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg10]HOE 140, which has bradykinin B1 antagonist activity[1].

Molecular Weight

391.46

Formula

C24H25NO4
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (255.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5545 mL 12.7727 mL 25.5454 mL
5 mM 0.5109 mL 2.5545 mL 5.1091 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.72%

SDS (393 KB)

COA (260 KB) HNMR (125 KB) RP-HPLC (184 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5545 mL 12.7727 mL 25.5454 mL 63.8635 mL
5 mM 0.5109 mL 2.5545 mL 5.1091 mL 12.7727 mL
10 mM 0.2555 mL 1.2773 mL 2.5545 mL 6.3863 mL
15 mM 0.1703 mL 0.8515 mL 1.7030 mL 4.2576 mL
20 mM 0.1277 mL 0.6386 mL 1.2773 mL 3.1932 mL
25 mM 0.1022 mL 0.5109 mL 1.0218 mL 2.5545 mL
30 mM 0.0852 mL 0.4258 mL 0.8515 mL 2.1288 mL
40 mM 0.0639 mL 0.3193 mL 0.6386 mL 1.5966 mL
50 mM 0.0511 mL 0.2555 mL 0.5109 mL 1.2773 mL
60 mM 0.0426 mL 0.2129 mL 0.4258 mL 1.0644 mL
80 mM 0.0319 mL 0.1597 mL 0.3193 mL 0.7983 mL
100 mM 0.0255 mL 0.1277 mL 0.2555 mL 0.6386 mL
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Fmoc-Oic-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-Oic-OH130309-37-4Amino Acid DerivativesProtecting groupspeptide synthesisderivativesamino acidsInhibitorinhibitorinhibit

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