2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Fmoc-Phe-Lys(Trt)-PAB-PNP

Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Fmoc-Phe-Lys(Trt)-PAB-PNP Chemical Structure

Fmoc-Phe-Lys(Trt)-PAB-PNP Chemical Structure

CAS No. : 1116086-09-9

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Fmoc-Phe-Lys(Trt)-PAB-PNP Related Antibodies

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Description

Fmoc-Phe-Lys(Trt)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Protease Cleavable Linker

 

Cleavable Linker

 

Molecular Weight

1028.15

Formula

C63H57N5O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N)[C@H](CCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)N(C([C@H](CC4=CC=CC=C4)NC(OCC5C6=C(C7=C5C=CC=C7)C=CC=C6)=O)=O)C8=CC=C(COC(OC9=CC=C([N+]([O-])=O)C=C9)=O)C=C8
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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Fmoc-Phe-Lys(Trt)-PAB-PNP Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-Phe-Lys(Trt)-PAB-PNP1116086-09-9ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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