2. PROTAC
  3. PROTAC Linkers
  4. Folate-PEG3-NHS ester

Folate-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Folate-PEG3-NHS ester Chemical Structure

Folate-PEG3-NHS ester Chemical Structure

Size Price Stock Quantity
1 mg USD 200 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
5 mg USD 515 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
10 mg USD 825 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
25 mg USD 1650 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
50 mg USD 2650 Get quote 3 - 4 weeks 4 - 5 weeks 2 - 3 weeks
100 mg   Get quote  
200 mg   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

Folate-PEG3-NHS ester Related Antibodies

Top Publications Citing Use of Products

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  • Biological Activity

  • Purity & Documentation

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Description

Folate-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Folate-PEG3-NHS ester Related Antibodies
Molecular Weight

741.71

Formula

C32H39N9O12
SMILES

NC(NC1=O)=NC2=C1N=C(C=N2)CNC3=CC=C(C(N[C@@H](CCC(NCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O)=O)C(O)=O)=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Folate-PEG3-NHS ester Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Folate-PEG3-NHS esterPROTAC LinkersInhibitorinhibitorinhibit

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Product Name:
Folate-PEG3-NHS ester
Cat. No.:
HY-133493
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