2. Immunology/Inflammation
  3. CD3
  4. Forimtamig

Forimtamig  (Synonyms: RG-6324; RO-7425781)

Cat. No.: HY-P991055
Technical Support

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

Forimtamig Chemical Structure

Forimtamig Chemical Structure

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Forimtamig Related Antibodies

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Description

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001)[1].

SMILES

[Forimtamig]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Forimtamig Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ForimtamigRG-6324 RO-7425781RG6324RG 6324RO7425781RO 7425781RO-7425781CD3Cluster of differentiation 3GPRC5DxCD3 T-cell-engaging bispecific antibodyInhibitorinhibitorinhibit

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