2. Anti-infection
  3. Fungal
  4. Fosmanogepix (tautomerism)

Fosmanogepix (tautomerism)  (Synonyms: APX001 (tautomerism); E1211 (tautomerism))

Cat. No.: HY-119726A
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Fosmanogepix tautomerism (APX001 tautomerism) is a broad-spectrum and orally active anti-invasive fungal compound. Fosmanogepix tautomerism targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi, and inhibition prevents proper localization of cell wall mannoproteins, thereby impairing cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix tautomerism can be used to study invasive fungal infections.

For research use only. We do not sell to patients.

Fosmanogepix (tautomerism) Chemical Structure

Fosmanogepix (tautomerism) Chemical Structure

CAS No. : 1169701-00-1

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Other Forms of Fosmanogepix (tautomerism):

Fosmanogepix (tautomerism) Related Antibodies

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Description

Fosmanogepix tautomerism (APX001 tautomerism) is a broad-spectrum and orally active anti-invasive fungal compound. Fosmanogepix tautomerism targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi, and inhibition prevents proper localization of cell wall mannoproteins, thereby impairing cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix tautomerism can be used to study invasive fungal infections[1].

Molecular Weight

468.40

Formula

C22H21N4O6P
CAS No.
SMILES

N=C1C(C2=CC(CC3=CC=C(C=C3)COC4=NC=CC=C4)=NO2)=CC=CN1COP(O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Fosmanogepix (tautomerism) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fosmanogepix (tautomerism)1169701-00-1APX001 (tautomerism) E1211 (tautomerism)FungalFungal infectioninvasivenesscell wallmannoproteinlocalizationInhibitorinhibitorinhibit

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