1. Metabolic Enzyme/Protease
  2. Acyltransferase
  3. FR186054

FR186054 is an oral active acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with the IC50 of 99 nM. FR186054 shows hypocholesterolemic effect and can be used for study of hypercholesterolemia and atherosclerosis.

For research use only. We do not sell to patients.

FR186054 Chemical Structure

FR186054 Chemical Structure

CAS No. : 179053-90-8

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Description

FR186054 is an oral active acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor with the IC50 of 99 nM. FR186054 shows hypocholesterolemic effect and can be used for study of hypercholesterolemia and atherosclerosis[1][2].

Molecular Weight

489.66

Formula

C26H27N5OS2

CAS No.
SMILES

O=C(N(CC1=CC=CC(C2=NNC=C2)=C1)CC3=CC=CC=C3)NC4=C(SC)N=C(C)C=C4SC

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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FR186054
Cat. No.:
HY-117466
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