2. Anti-infection
  3. Antibiotic Bacterial
  4. Framycetin (sulfate) (Standard)

Framycetin (sulfate) (Standard) 

Cat. No.: HY-17624AR Purity: ≥98%
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Framycetin (sulfate) (Standard) is the analytical standard of Framycetin (sulfate). This product is intended for research and analytical applications. Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.

For research use only. We do not sell to patients.

Framycetin (sulfate) (Standard) Chemical Structure

Framycetin (sulfate) (Standard) Chemical Structure

CAS No. : 4146-30-9

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Description

Framycetin (sulfate) (Standard) is the analytical standard of Framycetin (sulfate). This product is intended for research and analytical applications. Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.

Molecular Weight

908.88

Formula

C23H52N6O25S3
CAS No.
SMILES

O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.N[C@@H](C[C@H]1N)[C@@]([C@@H]([C@H]1O)O[C@@](O[C@H](CO)[C@H]2O[C@@]([C@@H]([C@@H](O)[C@@H]3O)N)([H])O[C@H]3CN)([H])[C@@H]2O)([H])O[C@H]([C@@H]([C@@H](O)[C@@H]4O)N)O[C@@H]4CN
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Framycetin (sulfate) (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Framycetin (sulfate) (Standard)4146-30-9AntibioticBacterialantibioticRNasePcleavagedivalentmetalionhammerheadribozyme5″-azidoneomycinBDroshamiR-525hepaticencephalopathyE.coliInhibitorinhibitorinhibit

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