2. Vitamin D Related/Nuclear Receptor Autophagy Apoptosis
  3. Estrogen Receptor/ERR Autophagy Apoptosis
  4. Fulvestrant (Standard)

Fulvestrant (Standard)  (Synonyms: ICI 182780(Standard); ZD 9238(Standard); ZM 182780 (Standard))

Cat. No.: HY-13636R Purity: 99.71%
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Fulvestrant (Standard) is the analytical standard of Fulvestrant. This product is intended for research and analytical applications. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

For research use only. We do not sell to patients.

Fulvestrant (Standard) Chemical Structure

Fulvestrant (Standard) Chemical Structure

CAS No. : 129453-61-8

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This product is a controlled substance and not for sale in your territory.

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Description
Molecular Weight

606.77

Formula

C₃₂H₄₇F₅O₃S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Fulvestrant (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fulvestrant (Standard)129453-61-8ICI 182780(Standard) ZD 9238(Standard) ZM 182780 (Standard)Estrogen Receptor/ERRAutophagyApoptosisInhibitorinhibitorinhibit

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