2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. G-quadruplex ligand 2

G-quadruplex ligand 2 (compound A3) is a triphenylamine-based ligand that targets mitochondrial DNA G4s. G-quadruplex ligand 2 activates the cGAS-STING pathway. G-quadruplex ligand 2 inhibits tumor growth and metastasis via regulation of TME.

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G-quadruplex ligand 2 Chemical Structure

G-quadruplex ligand 2 Chemical Structure

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G-quadruplex ligand 2 Related Antibodies

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Description

G-quadruplex ligand 2 (compound A3) is a triphenylamine-based ligand that targets mitochondrial DNA G4s. G-quadruplex ligand 2 activates the cGAS-STING pathway. G-quadruplex ligand 2 inhibits tumor growth and metastasis via regulation of TME[1].

Molecular Weight

666.59

Formula

C37H35IN2O2
SMILES

COC1=CC=C(C=C1)N(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)/C=C/C4=[N+](C5=C(C4(C)C)C6=C(C=C5)C=CC=C6)C.[I-]
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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G-quadruplex ligand 2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

G-quadruplex ligand 2DNA/RNA Synthesismitochondrial DNA G4sTMEInhibitorinhibitorinhibit

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G-quadruplex ligand 2
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HY-158126
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