2. Metabolic Enzyme/Protease
  3. Proteasome Factor Xa
  4. Gabexate mesylate (Standard)

Gabexate mesylate (Standard) 

Cat. No.: HY-B0385R Purity: ≥98%
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Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation.

For research use only. We do not sell to patients.

Gabexate mesylate (Standard) Chemical Structure

Gabexate mesylate (Standard) Chemical Structure

CAS No. : 56974-61-9

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Description

Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation.

Molecular Weight

417.48

Formula

C17H27N3O7S
CAS No.
SMILES

O=C(OCC)C1=CC=C(OC(CCCCCNC(N)=N)=O)C=C1.CS(=O)(O)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Gabexate mesylate (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gabexate mesylate (Standard)56974-61-9ProteasomeFactor XaFxaCompetitivenon-antigenictrypsin-like serine proteinasethrombinurokinaseplasmintryptaseanticoagulantanti-inflammatoryviainhibitionNF-κBproinflammatory cytokinesnitric oxidepancreatitisdisseminated intravascular coagulationInhibitorinhibitorinhibit

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