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  4. Gadoteric acid

Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution.

For research use only. We do not sell to patients.

Gadoteric acid Chemical Structure

Gadoteric acid Chemical Structure

CAS No. : 72573-82-1

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Based on 1 publication(s) in Google Scholar

Gadoteric acid Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution[1][2].

In Vitro

Gadoteric acid provides superior contrast and conspicuity of hepatocellular carcinoma (especially hypervascular lesions) in DCE-MRI in terms of better perceptibility of early enhancement and a stronger washout[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gadoteric acid Related Antibodies
Clinical Trial
Molecular Weight

558.64

Formula

C16H25GdN4O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1[O-][Gd+3]([N](CC2)(CC3)CC4=O)([N]53CC6=O)([N]72C1)([O-]6)([O-]4)([O-]8)[N](CC7)(CC5)CC8=O.[H+]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (179.01 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7901 mL 8.9503 mL 17.9006 mL
5 mM 0.3580 mL 1.7901 mL 3.5801 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

SDS (393 KB)

COA (263 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7901 mL 8.9503 mL 17.9006 mL 44.7515 mL
5 mM 0.3580 mL 1.7901 mL 3.5801 mL 8.9503 mL
10 mM 0.1790 mL 0.8950 mL 1.7901 mL 4.4752 mL
15 mM 0.1193 mL 0.5967 mL 1.1934 mL 2.9834 mL
20 mM 0.0895 mL 0.4475 mL 0.8950 mL 2.2376 mL
25 mM 0.0716 mL 0.3580 mL 0.7160 mL 1.7901 mL
30 mM 0.0597 mL 0.2983 mL 0.5967 mL 1.4917 mL
40 mM 0.0448 mL 0.2238 mL 0.4475 mL 1.1188 mL
50 mM 0.0358 mL 0.1790 mL 0.3580 mL 0.8950 mL
60 mM 0.0298 mL 0.1492 mL 0.2983 mL 0.7459 mL
80 mM 0.0224 mL 0.1119 mL 0.2238 mL 0.5594 mL
100 mM 0.0179 mL 0.0895 mL 0.1790 mL 0.4475 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Gadoteric acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gadoteric acid72573-82-1Biochemical Assay Reagentsparamagneticcontrast agentMRIvascular distributionbrainspineInhibitorinhibitorinhibit

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