2. Immunology/Inflammation
  3. Galectin
  4. Galectin-3/galectin-8-IN-2

Galectin-3/galectin-8-IN-2 (Compound 57) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 12.8 μM and 2.06 μM respectively. Galectin-3/galectin-8-IN-2 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-2 can be used for research of cancer and tissue fibrosis.

For research use only. We do not sell to patients.

Galectin-3/galectin-8-IN-2 Chemical Structure

Galectin-3/galectin-8-IN-2 Chemical Structure

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Galectin-3/galectin-8-IN-2 Related Antibodies

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Description

Galectin-3/galectin-8-IN-2 (Compound 57) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 12.8 μM and 2.06 μM respectively. Galectin-3/galectin-8-IN-2 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-2 can be used for research of cancer and tissue fibrosis[1].

IC50 & Target

Kd: 12.8 μM (Galectin-3) and 2.06 μM (Galectin-8C)[1]
Molecular Weight

557.47

Formula

C26H18Cl2N2O4S2
SMILES

O=C(C(N1)=CC2=C1C=CC(OC3=CC=C(Cl)C(Cl)=C3)=C2)NS(=O)(C4=C(CC5=CC=CC=C5)C=CS4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Galectin-3/galectin-8-IN-2 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Galectin-3/galectin-8-IN-2GalectinmigrationMRC-5lungfibroblastcancerfibrosisInhibitorinhibitorinhibit

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