2. Anti-infection
  3. Bacterial
  4. Ganfeborole

Ganfeborole  (Synonyms: GSK656 free base; GSK3036656 free base; GSK070 free base)

Cat. No.: HY-134648
Handling Instructions

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Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Ganfeborole hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Ganfeborole Chemical Structure

Ganfeborole Chemical Structure

CAS No. : 2131798-12-2

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Ganfeborole Related Antibodies

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Description

Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis[1].

Clinical Trial
Molecular Weight

257.48

Formula

C10H13BClNO4
CAS No.
SMILES

OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ganfeborole Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganfeborole2131798-12-2GSK656GSK3036656GSK070GSK 656GSK-656GSK 3036656GSK-3036656GSK 070GSK-070BacterialM. tuberculosisleucyl-tRNA synthetasetuberculosisInhibitorinhibitorinhibit

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