2. Membrane Transporter/Ion Channel
  3. Chloride Channel
  4. GaTx2

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types.

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GaTx2 Chemical Structure

GaTx2 Chemical Structure

CAS No. : 194665-85-5

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100 μg USD 550 In-stock

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Based on 1 publication(s) in Google Scholar

GaTx2 Related Antibodies

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Description

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types[1].

IC50 & Target

Kd: 20 pM (ClC-2 channel)[1]
Molecular Weight

3192.54

Formula

C125H199N39O47S6
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

VSCEDCPDHCSTQKARAKCDNDKCVCEPI (Disulfide bridge:Cys3-Cys19;Cys6-Cys24;Cys10-Cys26)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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GaTx2 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GaTx2194665-85-5GaTx 2GaTx-2Chloride ChannelCl− ChannelsmembranelocalizationClC-2blockertoxinClC familyInhibitorinhibitorinhibit

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