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GEA 3162, oxatriazol derivative, is a NO-releasing compound. GEA 3162 can be used for the research of Inflammation diseases.

For research use only. We do not sell to patients.

GEA 3162 Chemical Structure

GEA 3162 Chemical Structure

CAS No. : 144576-10-3

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GEA 3162 Related Antibodies

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Description

GEA 3162, oxatriazol derivative, is a NO-releasing compound. GEA 3162 can be used for the research of Inflammation diseases[1].

In Vitro

GEA 3162 (1-100 μM) inhibits Ca ionophore A23187-induced LTB4 and beta-glucuronidase release, chemotactic peptide FMLP-induced chemotaxis and opsonized zymosan-triggered chemiluminescence dose-dependently in human PMNs[1].
GEA 3162 (0-1 mM) inhibits LTB4 release from human PMNs dose-dependently[1].
GEA 3162 (0-1 mM) suppresses β-glucuronidase release from A23187-activated PMNs dose-dependently[1].
GEA 3162 (0-1 mM) is effective inhibitor of FMLP-induced chemotactic movement of human PMNs with IC50 value of 6 μM[1].
GEA 3162 increases the cyclic GMP levels more rapidly and at lower drug concentrations[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GEA 3162 Related Antibodies
Molecular Weight

231.04

Formula

C7H4Cl2N4O
CAS No.
SMILES

ClC1=CC=C([N+]2=NOC([NH-])=N2)C=C1Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GEA 3162 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GEA 3162144576-10-3GEA3162GEA-3162Othersoxatriazol derivativeNOInflammation diseasesInhibitorinhibitorinhibit

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