IZUMO3 - IZUMO family member 3 Gene

Homo sapiens

Also known as C9orf134; bA20A20.1

Gene ID: 100129669 | Gene type: protein coding

About IZUMO3

Cytogenetic location: 9p21.3 Genomic coordinates (GRCh38): 9:24,542,952-24,545,897 (from NCBI)

This gene has 3 transcripts (splice variants) and 83 orthologues. Restricted expression toward testis (RPKM 4.9).

Summary

Predicted to enable protein homodimerization activity. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

IZUMO3 Products(2)

mRNA	Protein	Name
NM_001271706.1	NP_001258635.1	izumo sperm-egg fusion protein 3 isoform 1 precursor
NM_001365008.2	NP_001351937.1	izumo sperm-egg fusion protein 3 isoform 2 precursor

IZUMO3 Protein Structure

IZUMO

0
100
200
239 a.a.

Protein Preferred Names

Protein Names

izumo sperm-egg fusion protein 3

Related Diseases

Diseases

Alias

Calvarial Doughnut Lesions With Bone Fragility

Calvarial Doughnut Lesions With Bone Fragility With Or Without Spondylometaphyseal Dysplasia	Calvarial Doughnut Lesions-Bone Fragility Syndrome
CDL	Doughnut Lesions Of Skull, Familial
Calvarial Doughnut Lesions With Bone Fragility And Spondylometaphyseal Dysplasia	Familial Doughnut Lesions Of Skull
CDLSMD

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07007	IZUMO3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	IZUMO3	MGD	MGI:1916564
Felis catus	IZUMO3	VGNC	VGNC:62993
Canis familiaris	IZUMO3	VGNC	VGNC:42167
Bos taurus	IZUMO3	VGNC	VGNC:30356
Rattus norvegicus	IZUMO3	RGD	RGD:2324467

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