CDH9 - cadherin 9 Gene

Homo sapiens

Gene ID: 1007 | Gene type: protein coding

About CDH9

Cytogenetic location: 5p14.1 Genomic coordinates (GRCh38): 5:26,880,597-27,038,586 (from NCBI)

This gene has 5 transcripts (splice variants), 133 orthologues and 33 paralogues. Biased expression in brain (RPKM 3.5) and kidney (RPKM 1.9).

Summary

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) Cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I Cadherins. [provided by RefSeq, Jul 2008]

CDH9 Products(1)

mRNA	Protein	Name
NM_016279.4	NP_057363.3	cadherin-9 preproprotein

CDH9 Protein Structure

Cadherin

Cadherin_C

0
200
400
600
789 a.a.

Protein Preferred Names

Protein Names

cadherin-9

T1-cadherin

Recombinant CDH9 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P78770	Cadherin-9/CDH9 Protein, Human (HEK293, His)	Q9ULB4-1 (G54-A615)	≥95%

Related Diseases

Diseases

Alias

Craniofacial-Deafness-Hand Syndrome

CDHS	Craniofacial Deafness Hand Syndrome
Sommer-Young-Wee-Frye Syndrome	Features Of Flat Facial Profile, Hypertelorism, Hypoplastic Nose With Slitlike Nares, And A Sensorineural Hearing Loss
Craniofacial-Hearing Loss-Hand Syndrome

Childhood Disintegrative Disease

Childhood Disintegrative Disorder	Disintegrative Psychosis
Heller'S Syndrome	Symbiotic Psychosis
Dementia Infantilis	Heller Syndrome
Shared Paranoid Disorder

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy	Benign Rolandic Epilepsy
Epilepsy, Rolandic	Bcects
Benign Childhood Epilepsy With Centrotemporal Spike	Sylvan Seizures
Becrs	Bects
Bre	Benign Epilepsy Of Childhood With Centrotemporal Spikes
Benign Familial Epilepsy Of Childhood With Rolandic Spikes	Centrotemporal Epilepsy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02342	CDH9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CDH9	VGNC	VGNC:27107
Mus musculus	CDH9	MGD	MGI:107433
Felis catus	CDH9	VGNC	VGNC:60687
Macaca mulatta	CDH9	VGNC	VGNC:70977
Canis familiaris	CDH9	VGNC	VGNC:39036
Rattus norvegicus	CDH9	RGD	RGD:1308343
Others	CDH9	NCBI

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