TENM1 - teneurin transmembrane protein 1 Gene

Homo sapiens

Also known as TNM; ODZ1; ODZ3; TEN1; TNM1; ten-1; TEN-M1

Gene ID: 10178 | Gene type: protein coding

About TENM1

Cytogenetic location: Xq25 Genomic coordinates (GRCh38): X:124,375,903-125,204,312 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues, 4 paralogues and is associated with 1 phenotype. Broad expression in prostate (RPKM 2.1), brain (RPKM 2.0) and 17 other tissues.

Summary

The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

TENM1 Products(3)

mRNA	Protein	Name
NM_001163278.2	NP_001156750.1	teneurin-1 isoform 1 precursor
NM_001163279.1	NP_001156751.1	teneurin-1 isoform 2 precursor
NM_014253.3	NP_055068.2	teneurin-1 isoform 3 precursor

TENM1 Protein Structure

Ten_N

hEGF

Tox-GHH

0
500
1000
1500
2000
2500
2725 a.a.

Protein Preferred Names

Protein Names

teneurin-1

odz (odd Oz/ten-m, Drosophila) homolog 3

Related Diseases

Diseases

Alias

Anosmia, Isolated Congenital

ANIC	Isolated Congenital Anosmia
Anosmia, Congenital	Congenital Anosmia

Anal Margin Carcinoma

Carcinoma Of Anal Margin

Perianal Skin Carcinoma

Anal Canal Carcinoma

Anal Canal Cancer	Anal Canal And Perianal Gland Carcinoma
Carcinoma Of The Anal Canal	Carcinoma Of Anal Canal

Microphthalmia

Microphthalmos	Isolated Anophthalmia-Microphthalmia Syndrome
Isolated Microphthalmia-Anophthalmia-Coloboma	Simple Microphthalmos
Clinical Anophthalmia	Isolated Anophthalmia - Microphthalmia
Isolated Pure Microphthalmia	Mac Spectrum
Microphthalmia-Anophthalmia-Coloboma Spectrum	Primitive Anophthalmia
Globe Of Eye Small	Small Eyeball
Hypoplasia Of Eye	Isolated Nanophthalmos
Rudimentary Eye	Dysplasia Of Eye

Cerebral Palsy

Infantile Cerebral Palsy	Mixed Cerebral Palsy
Palsy Cerebral	Palsy, Cerebral
Cerebral Palsy, Mixed

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14362	TENM1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TENM1	VGNC	VGNC:47246
Mus musculus	TENM1	MGD	MGI:1345185
Felis catus	TENM1	VGNC	VGNC:68620
Rattus norvegicus	TENM1	RGD	RGD:1561678
Macaca mulatta	TENM1	VGNC	VGNC:79969
Bos taurus	TENM1	VGNC	VGNC:35741

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