2. Gene
  3. LRRC17 - leucine rich repeat containing 17 Gene

LRRC17 - leucine rich repeat containing 17 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as P37NB

Gene ID: 10234 | Gene type: protein coding

About LRRC17

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:102,913,000-102,945,111 (from NCBI)

This gene has 5 transcripts (splice variants), 248 orthologues and 22 paralogues. Biased expression in ovary (RPKM 29.2), gall bladder (RPKM 13.5) and 10 other tissues.

Summary

Predicted to be involved in bone marrow development and negative regulation of osteoclast differentiation. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LRRC17 Products(2)

mRNA Protein Name
NM_001031692.3 NP_001026862.1 leucine-rich repeat-containing protein 17 isoform 1 precursor
NM_005824.3 NP_005815.2 leucine-rich repeat-containing protein 17 isoform 2 precursor

LRRC17 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (87 - 141)

LRR_8

LRR_8: Leucine rich repeat (293 - 350)

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  • 441 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 17

37 kDa leucine-rich repeat (LRR) protein

Related Diseases

Diseases Alias
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07809 LRRC17 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LRRC17 VGNC VGNC:63289
Canis familiaris LRRC17 VGNC VGNC:51879
Mus musculus LRRC17 MGD MGI:1921761
Rattus norvegicus LRRC17 RGD RGD:1560165
Bos taurus LRRC17 VGNC VGNC:52798
Macaca mulatta LRRC17 VGNC VGNC:74301