2. Gene
  3. IGSF6 - immunoglobulin superfamily member 6 Gene

IGSF6 - immunoglobulin superfamily member 6 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DORA

Gene ID: 10261 | Gene type: protein coding

About IGSF6

Cytogenetic location: 16p12.2 Genomic coordinates (GRCh38): 16:21,639,550-21,652,608 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele and 122 orthologues. Biased expression in spleen (RPKM 32.0), appendix (RPKM 25.4) and 13 other tissues.

Summary

Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IGSF6 Products(1)

mRNA Protein Name
NM_005849.4 NP_005840.2 immunoglobulin superfamily member 6 precursor

IGSF6 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (43 - 141)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

immunoglobulin superfamily member 6

down-regulated by activation (immunoglobulin superfamily)

Related Diseases

Diseases Alias
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
Inflammatory Bowel Disease 1

Inflammatory Bowel Disease 1

IBD1

Crohn Disease-Associated Growth Failure

Crohn Disease

Regional Enteritis

Ulcerative Colitis

Crohn Disease-Associated Growth Failure, Susceptibility To

Inflammatory Bowel Disease 1, Crohn Disease

Bowel Disease, Inflammatory, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06650 IGSF6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris IGSF6 VGNC VGNC:41917
Macaca mulatta IGSF6 VGNC VGNC:73701
Rattus norvegicus IGSF6 RGD RGD:620663
Mus musculus IGSF6 MGD MGI:1891393
Bos taurus IGSF6 VGNC VGNC:30095