2. Gene
  3. CLGN - calmegin Gene

CLGN - calmegin Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 1047 | Gene type: protein coding

About CLGN

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:140,388,453-140,427,648 (from NCBI)

This gene has 3 transcripts (splice variants), 194 orthologues and 3 paralogues. Biased expression in testis (RPKM 66.0), heart (RPKM 22.6) and 2 other tissues.

Summary

Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility. [provided by RefSeq, Jul 2008]

CLGN Products(2)

mRNA Protein Name
NM_001130675.2 NP_001124147.1 calmegin precursor
NM_004362.3 NP_004353.1 calmegin precursor

CLGN Protein Structure

Calreticulin

Calreticulin: Calreticulin family (60 - 429)

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  • 610 a.a.
Protein Preferred Names Protein Names

calmegin

testis tissue sperm-binding protein Li 79P

Recombinant CLGN Proteins

Cat. No. Product Name Accession Purity
HY-P7709 Calmegin/CLGN Protein, Human (HEK293, His) O14967-1 (E20-W471) ≥95%

Related Diseases

Diseases Alias
Colloid Adenoma

Macrofollicular Adenoma
Carotid Artery Dissection

Dissection Of Carotid Artery
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02802 CLGN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CLGN VGNC VGNC:60957
Mus musculus CLGN MGD MGI:107472
Macaca mulatta CLGN VGNC VGNC:71253
Rattus norvegicus CLGN RGD RGD:1592643
Canis familiaris CLGN VGNC VGNC:39336
Bos taurus CLGN VGNC VGNC:27437
Others CLGN NCBI