2. Gene
  3. Slc14a1 - solute carrier family 14 (urea transporter), member 1 Gene

Slc14a1 - solute carrier family 14 (urea transporter), member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as UT-B; Utb1; 2610507K20Rik; 3021401A05Rik

Gene ID: 108052 | Gene type: protein coding

About Slc14a1

Summary

Enables urea transmembrane transporter activity and water transmembrane transporter activity. Acts upstream of or within urea transport and water transport. Located in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; limb; musculature; and sensory organ. Orthologous to human SLC14A1 (solute carrier family 14 member 1 (Kidd blood group)). [provided by Alliance of Genome Resources, Apr 2022]

Slc14a1 Products(3)

mRNA Protein Name
NM_001171010.1 NP_001164481.1 urea transporter 1 isoform a
NM_001171011.1 NP_001164482.1 urea transporter 1 isoform b
NM_028122.4 NP_082398.1 urea transporter 1 isoform b
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables urea transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
11792714 MGI
enables water transmembrane transporter activity IDA
IDA: Inferred from direct assay
11792714 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within establishment of localization in cell IGI
IGI: Inferred from genetic interaction
12133842 MGI
acts upstream of or within urea transport IMP
IMP: Inferred from mutant phenotype
11792714 MGI
acts upstream of or within water transport IDA
IDA: Inferred from direct assay
11792714 MGI
acts upstream of or within water transport IGI
IGI: Inferred from genetic interaction
12133842 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
15563580 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12133842 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

urea transporter 1

solute carrier family 14 member 1

urea transporter B

urea transporter, erythrocyte

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16218 SLC14A1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13010 SLC14A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc14a1 NCBI NCBI:6563