Grm2 - glutamate receptor, metabotropic 2 Gene

Mus musculus

Also known as Gprc1b; mGluR2; mGluR7; 4930441L02Rik

Gene ID: 108068 | Gene type: protein coding

About Grm2

Chromosome 9: 106,520,294-106,533,281 reverse strand.GRCm39:CM001002.3

This gene has 4 transcripts (splice variants), 280 orthologues, 7 paralogues and is associated with 10 phenotypes. Biased expression in frontal lobe adult (RPKM 23.), cortex adult (RPKM 16.8) and 6 other tissues.

Summary

Enables Calcium Channel regulator activity and group II metabotropic glutamate receptor activity. Acts upstream of or within chemical synaptic transmission; gene expression; and glutamate homeostasis. Located in neuron projection. Is expressed in brain. Orthologous to human GRM2 (glutamate metabotropic receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Grm2 Products(1)

mRNA	Protein	Name
NM_001160353.1	NP_001153825.1	metabotropic glutamate receptor 2 precursor

Grm2 Protein Structure

PBP1_mGluR_groupII

NCD3G

7tmC_mGluR2

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400
600
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872 a.a.

Protein Preferred Names

Protein Names

metabotropic glutamate receptor 2

G protein-coupled receptor, family C, group 1, member B

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05822	GRM2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS05823	Grm2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS05824	Grm2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Grm2	NCBI	NCBI:2912

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