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  2. Grm7 - glutamate receptor, metabotropic 7 Gene

Grm7 - glutamate receptor, metabotropic 7 Gene

Mus musculus

Also known as SMN2; Gpr1g; Gprc1g; mGluR7; C030018L03; 6330570A01Rik; E130018M02Rik; Tg(SMN2)89Ahmb

Gene ID: 108073 | Gene type: protein coding

About Grm7

Chromosome 6: 110,622,542-111,544,191 forward strand.GRCm39:CM000999.3

This gene has 5 transcripts (splice variants), 280 orthologues, 7 paralogues and is associated with 22 phenotypes. Biased expression in cortex adult (RPKM 6.5), frontal lobe adult (RPKM 4.9) and 6 other tissues.

Summary

Enables Calcium Channel regulator activity and voltage-gated Calcium Channel activity. Involved in chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including behavioral fear response; learning or memory; and transmission of nerve impulse. Located in glutamatergic synapse and presynaptic membrane. Is expressed in several structures, including alimentary system; brain; eye; reproductive system; and spinal cord. Orthologous to human GRM7 (glutamate metabotropic receptor 7). [provided by Alliance of Genome Resources, Apr 2022]

Grm7 Products(2)

mRNA Protein Name
NM_001346640.1 NP_001333569.1 metabotropic glutamate receptor 7 isoform 2 precursor
NM_177328.3 NP_796302.2 metabotropic glutamate receptor 7 isoform 1 precursor

Grm7 Protein Structure

PBP1_mGluR_groupIII

PBP1_mGluR_groupIII: cd06376 (42 - 510)

NCD3G

NCD3G: pfam07562 (518 - 568)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (588 - 613)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (588 - 894)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (625 - 646)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (655 - 679)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (701 - 721)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (751 - 777)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (785 - 808)

7tmC_mGluR7

7tmC_mGluR7: cd15451 (818 - 843)

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  • 915 a.a.
Protein Preferred Names Protein Names

metabotropic glutamate receptor 7

G protein-coupled receptor GRM7

G protein-coupled receptor, family C, group 1, member G

mGlu7a receptor

Orthologs Information

Species Symbol Source ID
Homo sapiens Grm7 NCBI NCBI:2917