TSPAN9 - tetraspanin 9 Gene

Homo sapiens

Also known as NET5; NET-5; PP1057

Gene ID: 10867 | Gene type: protein coding

About TSPAN9

Cytogenetic location: 12p13.33-p13.32 Genomic coordinates (GRCh38): 12:3,077,379-3,286,559 (from NCBI)

This gene has 9 transcripts (splice variants), 271 orthologues and 32 paralogues. Broad expression in heart (RPKM 31.5), placenta (RPKM 20.4) and 23 other tissues.

Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]

TSPAN9 Products(2)

mRNA	Protein	Name
NM_001168320.2	NP_001161792.1	tetraspanin-9
NM_006675.5	NP_006666.1	tetraspanin-9

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	18795891	GOA
located in tetraspanin-enriched microdomain	IDA IDA: Inferred from direct assay	18795891	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPAN9 Protein Structure

Tetraspannin

0
100
200
239 a.a.

Protein Preferred Names

Protein Names

tetraspanin-9

new EST tetraspan 5

Related Diseases

Diseases

Alias

Fallopian Tube Carcinoma

Fallopian Tube Cancer	Cancer Of The Fallopian Tube
Carcinoma Of Fallopian Tube	Neoplasm Of Fallopian Tube
Fallopian Tube Neoplasms	Fallopian Tube Ca
Fallopian Tube Neoplasm	Malignant Neoplasm Of Uterine Tube
Malignant Tumor Of Fallopian Tube	Malignant Tumour Of Fallopian Tube
Tumor Of The Fallopian Tube	Tumor, Fallopian Tube, Malignant
Malignant Tumor Of Fallopian Tubes	Cancer Of Fallopian Tubes
Malignant Tubal Tumor	Tubal Cancer
Malignant Neoplasm Of Fallopian Tube	Primary Malignant Neoplasm Of Fallopian Tube
Cancer Of The Oviduct

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15175	TSPAN9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TSPAN9	VGNC	VGNC:100115
Felis catus	TSPAN9	VGNC	VGNC:66637
Canis familiaris	TSPAN9	VGNC	VGNC:47926
Mus musculus	TSPAN9	MGD	MGI:1924558
Rattus norvegicus	TSPAN9	RGD	RGD:1304740
Bos taurus	TSPAN9	VGNC	VGNC:36443

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