2. Gene
  3. ZNF277 - zinc finger protein 277 Gene

ZNF277 - zinc finger protein 277 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NRIF4; ZNF277P

Gene ID: 11179 | Gene type: protein coding

About ZNF277

Cytogenetic location: 7q31.1 Genomic coordinates (GRCh38): 7:112,206,695-112,343,934 (from NCBI)

This gene has 7 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in thyroid (RPKM 9.6), urinary bladder (RPKM 6.9) and 25 other tissues.

Summary

Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and metal ion binding activity. Predicted to act upstream of or within cellular response to hydrogen peroxide and regulation of cellular senescence. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF277 Products(1)

mRNA Protein Name
NM_021994.3 NP_068834.2 zinc finger protein 277

ZNF277 Protein Structure

zf-C2H2_2

zf-C2H2_2: C2H2 type zinc-finger (2 copies) (60 - 117)

zf-C2H2_2

zf-C2H2_2: C2H2 type zinc-finger (2 copies) (175 - 267)

zf-C2H2_2

zf-C2H2_2: C2H2 type zinc-finger (2 copies) (304 - 404)

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  • 450 a.a.
Protein Preferred Names Protein Names

zinc finger protein 277

nuclear receptor-interacting factor 4

Related Diseases

Diseases Alias
Specific Language Impairment

Language Impairment, Specific
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16117 ZNF277 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZNF277 VGNC VGNC:37237
Rattus norvegicus ZNF277 RGD RGD:1583856
Canis familiaris ZNF277 VGNC VGNC:48686
Felis catus ZNF277 VGNC VGNC:102734
Macaca mulatta ZNF277 VGNC VGNC:78890
Mus musculus ZNF277 MGD MGI:1890393