GLMP - glycosylated lysosomal membrane protein Gene

Homo sapiens

Also known as NCU-G1; C1orf85

Gene ID: 112770 | Gene type: protein coding

About GLMP

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,292,688-156,295,679 (from NCBI)

This gene has 16 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in prostate (RPKM 30.2), placenta (RPKM 24.2) and 25 other tissues.

Summary

Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; lysosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

GLMP Products(5)

mRNA	Protein	Name
NM_001256604.2	NP_001243533.1	glycosylated lysosomal membrane protein isoform 2 precursor
NM_001256605.2	NP_001243534.1	glycosylated lysosomal membrane protein isoform 3
NM_001256608.2	NP_001243537.1	glycosylated lysosomal membrane protein isoform 4 precursor
NM_001256609.2	NP_001243538.1	glycosylated lysosomal membrane protein isoform 5
NM_144580.3	NP_653181.1	glycosylated lysosomal membrane protein isoform 1 precursor

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	18021396	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	18021396	GOA
located in lysosome	IDA IDA: Inferred from direct assay	19556463	GOA
located in nucleus	IDA IDA: Inferred from direct assay	18021396	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GLMP Protein Structure

NCU-G1

0
100
200
300
406 a.a.

Protein Preferred Names

Protein Names

glycosylated lysosomal membrane protein

kidney lysosomal membrane protein

Related Diseases

Diseases

Alias

Multilocular Clear Cell Renal Cell Carcinoma

Cystadenocarcinoma Of Kidney

Renal Cystadenocarcinoma

Progressive Myoclonus Epilepsy 4

Action Myoclonus-Renal Failure Syndrome	Amrf
Epm4	Myoclonus-Nephropathy Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05484	GLMP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	GLMP	MGD	MGI:1913318
Felis catus	GLMP	VGNC	VGNC:62583
Macaca mulatta	GLMP	VGNC	VGNC:73030
Canis familiaris	GLMP	VGNC	VGNC:41265
Bos taurus	GLMP	VGNC	VGNC:29409
Rattus norvegicus	GLMP	RGD	RGD:1303130

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