Lyve1 - lymphatic vessel endothelial hyaluronan receptor 1 Gene

Mus musculus

Also known as Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik

Gene ID: 114332 | Gene type: protein coding

About Lyve1

Summary

Enables hyaluronic acid binding activity and transmembrane signaling receptor activity. Acts upstream of or within glycosaminoglycan catabolic process. Located in plasma membrane. Is expressed in several structures, including cardiovascular system; gut; hemolymphoid system; meninges; and metanephros. Orthologous to human LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lyve1 Products(1)

mRNA	Protein	Name
NM_053247.4	NP_444477.2	lymphatic vessel endothelial hyaluronic acid receptor 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables cargo receptor activity	IDA IDA: Inferred from direct assay	11278811	MGI
enables hyaluronic acid binding	IDA IDA: Inferred from direct assay	11278811	MGI
enables transmembrane signaling receptor activity	IDA IDA: Inferred from direct assay	11278811	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within glycosaminoglycan catabolic process	IDA IDA: Inferred from direct assay	11278811	MGI
involved in hyaluronan catabolic process	IDA IDA: Inferred from direct assay	11278811	MGI
involved in receptor-mediated endocytosis	IDA IDA: Inferred from direct assay	11278811	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell periphery	IDA IDA: Inferred from direct assay	16455951	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	11278811	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

lymphatic vessel endothelial hyaluronic acid receptor 1

cell surface retention sequence binding protein-1	extra cellular link domain-containing 1
extracellular link domain-containing protein 1	lymphatic vessel endothelial HA receptor-1
lymphatic vessel endothelial HA recptor-1

Recombinant Lyve1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74764	LYVE-1 Protein, Mouse (HEK293, Fc)	Q8BHC0 (A24-G228)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07929	LYVE1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lyve1	NCBI	NCBI:10894

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