2. Gene
  3. Bcl2l10 - Bcl2-like 10 Gene

Bcl2l10 - Bcl2-like 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 114552 | Gene type: protein coding

About Bcl2l10

Primary_assembly 8: 76,107,326-76,113,367 forward strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 132 orthologues, 13 paralogues and is associated with 7 phenotypes. Biased expression in Brain (RPKM 8.8), Adrenal (RPKM 4.9) and 7 other tissues.

Summary

Predicted to enable Caspase binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in oligodendrocyte differentiation. Predicted to be located in several cellular components, including cytosol; mitochondria-associated endoplasmic reticulum membrane; and mitochondrion. Predicted to be active in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Apr 2022]

Bcl2l10 Products(2)

mRNA Protein Name
NM_053733.1 NP_446185.1 bcl-2-like protein 10
NM_053733.1 NP_446185.1 bcl-2-like protein 10
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in oligodendrocyte differentiation IEP
IEP: Inferred from expression pattern
12787069 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Bcl2l10 Protein Structure

Bcl-2_like

Bcl-2_like: cd06845 (5 - 150)

  • 0
  • 100
  • 185 a.a.
Protein Preferred Names Protein Names

bcl-2-like protein 10

BCL2-like 10 (apoptosis facilitator)

anti-apoptotic protein Boo

apoptosis regulator Bcl-B

bcl2-L-10

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150540 Bcl-2-IN-10 / Unkown
HY-RS01424 BCL2L10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01425 Bcl2l10 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01426 Bcl2l10 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bcl2l10 NCBI NCBI:10017