2. Gene
  3. Hps1 - HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 Gene

Hps1 - HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hps

Gene ID: 114638 | Gene type: protein coding

About Hps1

Summary

Predicted to enable protein dimerization activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in lipid homeostasis; melanosome assembly; and protein secretion. Predicted to act upstream of or within with a negative effect on gene expression. Predicted to act upstream of or within several processes, including cellular zinc ion homeostasis; positive regulation of natural killer cell activation; and secretion of lysosomal Enzymes. Predicted to be located in cytoplasmic vesicle. Predicted to be part of BLOC-3 complex. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 1 and oculocutaneous albinism. Orthologous to human HPS1 (HPS1 biogenesis of lysosomal organelles complex 3 subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Hps1 Products(1)

mRNA Protein Name
NM_040669.1 NP_414541.1 Hermansky-Pudlak syndrome 1 protein
Protein Preferred Names Protein Names

Hermansky-Pudlak syndrome 1 protein

Hermansky-Pudlak syndrome 1 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06345 HPS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hps1 NCBI NCBI:3257
Macaca fascicularis Hps1 NCBI NCBI:102135630
Mus musculus Hps1 NCBI NCBI:192236