CARD16 - caspase recruitment domain family member 16 Gene

Homo sapiens

Also known as COP; COP1; PSEUDO-ICE; LLID-114769

Gene ID: 114769 | Gene type: protein coding

About CARD16

Cytogenetic location: 11q22.3 Genomic coordinates (GRCh38): 11:105,041,563-105,045,335 (from NCBI)

This gene has 5 transcripts (splice variants), 424 orthologues and 16 paralogues. Broad expression in spleen (RPKM 14.0), appendix (RPKM 12.0) and 23 other tissues.

Summary

Enables several functions, including CARD domain binding activity; cysteine-type endopeptidase inhibitor activity; and Enzyme binding activity. Involved in several processes, including negative regulation of cysteine-type endopeptidase activity; regulation of gene expression; and regulation of signal transduction. Part of Protease inhibitor complex. [provided by Alliance of Genome Resources, Apr 2022]

CARD16 Products(2)

mRNA	Protein	Name
NM_001394580.1	NP_001381509.1	caspase recruitment domain-containing protein 16 isoform 3
NM_052889.4	NP_443121.1	caspase recruitment domain-containing protein 16 isoform 2

CARD16 Protein Structure

CARD

0
100
197 a.a.

Protein Preferred Names

Protein Names

caspase recruitment domain-containing protein 16

CARD only domain-containing protein 1

Related Diseases

Diseases

Alias

Vestibulocochlear Nerve Disease

Vestibulocochlear Nerve Diseases	Acoustic Nerve Disease
Cochlear Nerve Diseases	Disturbance Of Vestibulocochlear Nerve
Auditory Nerve Disorder	Disorder Of Acoustovestibular Nerve
Disorder Of Eighth Nerve	Eighth Cranial Nerve Disorder
Disease Of Eighth Cranial Nerve	Disease Of Acoustic Nerve
Disease Of Auditory Nerve	Disorder Of 8th Cranial Nerve
Auditory Nerve Lesion	Cochlear Nerve Disorder

Vestibular Neuronitis

Vestibular Neuritis

Epidemic Neurolabyrinthitis

Colon Sarcoma

Colonic Sarcoma

Ehlers-Danlos Syndrome, Hypermobility Type

Ehlers-Danlos Syndrome, Type 3	Ehlers-Danlos Syndrome, Type Iii
EDSHMB	Eds Iii
Benign Hypermobility Syndrome	Ehlers-Danlos Syndrome Hypermobility Type
Eds3	Type Iii Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome Type 3	Es-D3

Huntington Disease

Huntington'S Disease	Huntington Chorea
Huntington'S Chorea	HD
Huntington Chronic Progressive Hereditary Chorea	Juvenile Huntington Disease
Chronic Progressive Chorea	Chronic Progressive Hereditary Chorea
Hc - [Huntington Chorea]	Hereditary Chorea
Progressive Hereditary Chorea

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01918	CARD16 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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