1. Gene
  2. CTHRC1 - collagen triple helix repeat containing 1 Gene

CTHRC1 - collagen triple helix repeat containing 1 Gene

Homo sapiens
Gene ID: 115908 | Gene type: protein coding

About CTHRC1

Cytogenetic location: 8q22.3 Genomic coordinates (GRCh38): 8:103,371,538-103,382,989 (from NCBI)

This gene has 4 transcripts (splice variants), 231 orthologues, 2 paralogues and is associated with 1 phenotype. Biased expression in gall bladder (RPKM 34.5), urinary bladder (RPKM 33.4) and 12 other tissues.

Summary

This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]

CTHRC1 Products(2)

mRNA Protein Name
NM_001256099.2 NP_001243028.1 collagen triple helix repeat-containing protein 1 isoform 2
NM_138455.4 NP_612464.1 collagen triple helix repeat-containing protein 1 isoform 1 precursor

CTHRC1 Protein Structure

Collagen

Collagen: Collagen triple helix repeat (20 copies) (58 - 91)

  • 0
  • 100
  • 200
  • 243 a.a.
Protein Preferred Names Protein Names

collagen triple helix repeat-containing protein 1

Recombinant CTHRC1 Proteins

Cat. No. Product Name Accession Purity
HY-P70092 CTHRC1 Protein, Human (HEK293, His) Q96CG8-1 (S31-K243) ≥95%

Related Diseases

Diseases Alias
Barrett Esophagus

Barrett'S Esophagus

Barrett Esophagus/Esophageal Adenocarcinoma

Barrett Metaplasia

Barrett'S Ulcer Of Esophagus

Ulcerative Esophagitis

Barrett'S Esophagus With Esophagitis

Barrett'S Oesophagus

Barretts Syndrome

Barrett Syndrome

BE

Peptic Ulcer Of Esophagus

Adenocarcinoma Of Esophagus

Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos

Bronchiectasis 1
Gastroesophageal Reflux

Gastroesophageal Reflux Disease

Gerd

GER

Gastroesophageal Reflux, Pediatric

Acid Reflux

Gastresophageal Reflux

Gastro-Esophageal Reflux

Gerd - Gastro-Esophageal Reflux Disease

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus CTHRC1 MGD MGI:1915838
Rattus norvegicus CTHRC1 RGD RGD:628801
Macaca mulatta CTHRC1 VGNC VGNC:71436
Felis catus CTHRC1 VGNC VGNC:61251
Bos taurus CTHRC1 VGNC VGNC:27796
Canis familiaris CTHRC1 VGNC VGNC:49728
Others CTHRC1 NCBI