2. Gene
  3. Angpt2 - angiopoietin 2 Gene

Angpt2 - angiopoietin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ang2; Agpt2; Ang-2

Gene ID: 11601 | Gene type: protein coding

About Angpt2

Summary

This gene encodes an endothelial cell (EC)-derived regulator of angiogenesis and ligand for endothelial-specific receptor tyrosine kinase. The encoded protein acts as an anti-apoptotic factor for stressed ECs and a proapoptotic factor for resting ECs. [provided by RefSeq, Jan 2013]

Angpt2 Products(1)

mRNA Protein Name
NM_007426.4 NP_031452.2 angiopoietin-2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9204896 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within angiogenesis IGI
IGI: Inferred from genetic interaction
16778080 MGI
acts upstream of or within blood vessel morphogenesis IMP
IMP: Inferred from mutant phenotype
15579434 MGI
acts upstream of or within negative regulation of angiogenesis IDA
IDA: Inferred from direct assay
9204896 MGI
acts upstream of or within negative regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
9846489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

angiopoietin-2

Recombinant Angpt2 Proteins

Cat. No. Product Name Accession Purity
HY-P7844 Angiopoietin-2 Protein, Mouse (HEK293, Fc) O35608 (Y19-F496) ≥95%
HY-P72830 Angiopoietin-2 Protein, Mouse (HEK293, His) O35608 (K275-F496) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00688 ANGPT2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990689 Zifibancimig / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Angpt2 NCBI NCBI:285
Canis familiaris Angpt2 NCBI NCBI:607616
Macaca fascicularis Angpt2 NCBI NCBI:101925495
Canis lupus familiaris Angpt2 NCBI
Macaca mulatta Angpt2 NCBI NCBI:716811