1. Gene
  2. IQCK - IQ motif containing K Gene

IQCK - IQ motif containing K Gene

Homo sapiens
Gene ID: 124152 | Gene type: protein coding

About IQCK

This gene has 15 transcripts (splice variants) and 125 orthologues. Broad expression in brain (RPKM 34.9), testis (RPKM 17.8) and 17 other tissues.

Summary

This gene belongs to the IQ motif-containing family of proteins. The IQ motif serves as a binding site for different EF-hand proteins such as Calmodulin. This gene was identified as a potential candidate gene for obsessive-compulsive disorder in a genome-wide association study. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

IQCK Products(6)

mRNA Protein Name
NM_001305121.3 NP_001292050.1 IQ domain-containing protein K isoform 2
NM_001305122.3 NP_001292051.1 IQ domain-containing protein K isoform 3
NM_001394804.1 NP_001381733.1 IQ domain-containing protein K isoform 1
NM_001394805.1 NP_001381734.1 IQ domain-containing protein K isoform 2
NM_001394806.1 NP_001381735.1 IQ domain-containing protein K isoform 4
NM_153208.3 NP_694940.1 IQ domain-containing protein K isoform 1
Protein Preferred Names Protein Names

IQ domain-containing protein K

Related Diseases

Diseases Alias
Obsessive-Compulsive Disorder

OCD

Obsessive-Compulsive Disorder, Susceptibility To

Anancastic Neurosis

Obsessive Compulsive Disorder

Anankastic Neurosis

Obsessive-Compulsive Neurosis

Obsessive Compulsive Behavior

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta IQCK VGNC VGNC:73671
Rattus norvegicus IQCK RGD RGD:6502881
Felis catus IQCK VGNC VGNC:80585
Bos taurus IQCK VGNC VGNC:58601
Mus musculus IQCK MGD MGI:3612188
Canis familiaris IQCK VGNC VGNC:54037