OVCA2 - OVCA2 serine hydrolase domain containing Gene

Homo sapiens

Gene ID: 124641 | Gene type: protein coding

About OVCA2

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:2,042,022-2,043,425 (from NCBI)

This gene has 1 transcript (splice variant) and 156 orthologues. Ubiquitous expression in adrenal (RPKM 23.0), gall bladder (RPKM 21.3) and 25 other tissues.

Summary

Involved in response to retinoic acid. Located in cytoplasm. Biomarker of ovarian Cancer. [provided by Alliance of Genome Resources, Apr 2022]

OVCA2 Products(1)

mRNA	Protein	Name
NM_080822.3	NP_543012.1	esterase OVCA2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in response to retinoic acid	IDA IDA: Inferred from direct assay	11979432	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	16368187	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OVCA2 Protein Structure

FSH1

0
100
200
227 a.a.

Protein Preferred Names

Protein Names

esterase OVCA2

candidate tumor suppressor in ovarian cancer 2

Related Diseases

Diseases

Alias

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09881	OVCA2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	OVCA2	MGD	MGI:2179725
Rattus norvegicus	OVCA2	RGD	RGD:1564623
Canis familiaris	OVCA2	VGNC	VGNC:44195
Bos taurus	OVCA2	VGNC	VGNC:32504

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