2. Gene
  3. Entpd1 - ectonucleoside triphosphate diphosphohydrolase 1 Gene

Entpd1 - ectonucleoside triphosphate diphosphohydrolase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cd39; NTPDase-1; 2610206B08Rik; E130009M23Rik

Gene ID: 12495 | Gene type: protein coding

About Entpd1

Summary

Enables adenosine-diphosphatase activity and nucleoside-triphosphatase activity. Involved in ADP catabolic process. Acts upstream of or within G protein-coupled receptor signaling pathway; platelet activation; and purine ribonucleoside diphosphate catabolic process. Located in basement membrane. Is active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 64. Orthologous to human ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Entpd1 Products(2)

mRNA Protein Name
NM_001304721.1 NP_001291650.1 ectonucleoside triphosphate diphosphohydrolase 1 isoform 1
NM_009848.4 NP_033978.1 ectonucleoside triphosphate diphosphohydrolase 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ADP phosphatase activity IMP
IMP: Inferred from mutant phenotype
17502665 MGI
enables nucleoside diphosphate phosphatase activity IDA
IDA: Inferred from direct assay
11929769 MGI
enables ribonucleoside triphosphate phosphatase activity IDA
IDA: Inferred from direct assay
11929769 MGI
Biological Process GO Annotation Evidence Reference Source
involved in ADP catabolic process IMP
IMP: Inferred from mutant phenotype
17502665 MGI
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
11929769 MGI
acts upstream of or within platelet activation IDA
IDA: Inferred from direct assay
11929769 MGI
acts upstream of or within purine ribonucleoside diphosphate catabolic process IDA
IDA: Inferred from direct assay
11929769 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
11929769 MGI
is active in external side of plasma membrane IMP
IMP: Inferred from mutant phenotype
17502665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ectonucleoside triphosphate diphosphohydrolase 1

CD39 antigen

NTPDase 1

ecto-ATP diphosphohydrolase 1

ecto-ATPDase 1

ecto-ATPase 1

ectoapyrase

lymphoid cell activation antigen

Recombinant Entpd1 Proteins

Cat. No. Product Name Accession Purity
HY-P70727 CD39 Protein, Mouse (HEK293, His) P55772 (T38-I478) ≥95%
HY-P72898 CD39 Protein, Mouse (His) P55772 (T38-I478) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04395 ENTPD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Entpd1 NCBI NCBI:953
Macaca mulatta Entpd1 NCBI