2. Gene
  3. TBC1D16 - TBC1 domain family member 16 Gene

TBC1D16 - TBC1 domain family member 16 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 125058 | Gene type: protein coding

About TBC1D16

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:79,932,343-80,035,872 (from NCBI)

This gene has 9 transcripts (splice variants), 206 orthologues and 45 paralogues. Ubiquitous expression in fat (RPKM 12.8), kidney (RPKM 8.0) and 23 other tissues.

Summary

Enables GTPase activator activity. Involved in regulation of receptor recycling. Located in cytosol and early endosome. [provided by Alliance of Genome Resources, Apr 2022]

TBC1D16 Products(4)

mRNA Protein Name
NM_001271844.2 NP_001258773.1 TBC1 domain family member 16 isoform b
NM_001271845.2 NP_001258774.1 TBC1 domain family member 16 isoform c
NM_001271846.2 NP_001258775.1 TBC1 domain family member 16 isoform d
NM_019020.4 NP_061893.2 TBC1 domain family member 16 isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
23019362 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22354992 GOA
Biological Process GO Annotation Evidence Reference Source
NOT involved in regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
17646400 GOA
involved in regulation of receptor recycling IDA
IDA: Inferred from direct assay
23019362 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytosol IDA
IDA: Inferred from direct assay
23019362 GOA
located in early endosome IDA
IDA: Inferred from direct assay
23019362 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TBC1D16 Protein Structure

RabGAP-TBC

RabGAP-TBC: Rab-GTPase-TBC domain (429 - 652)

  • 0
  • 200
  • 400
  • 600
  • 767 a.a.
Protein Preferred Names Protein Names

TBC1 domain family member 16

CTD-2529O21.1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14233 TBC1D16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TBC1D16 VGNC VGNC:65975
Bos taurus TBC1D16 VGNC VGNC:35630
Mus musculus TBC1D16 MGD MGI:2652878
Macaca mulatta TBC1D16 VGNC VGNC:78228
Rattus norvegicus TBC1D16 RGD RGD:1588560
Canis familiaris TBC1D16 VGNC VGNC:47135