2. Gene
  3. Cdh3 - cadherin 3 Gene

Cdh3 - cadherin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cadp; Cdhp; Pcad; P-cadherin

Gene ID: 12560 | Gene type: protein coding

About Cdh3

Summary

This gene encodes a calcium-dependent cell-cell adhesion protein containing five cadherin domains. The encoded protein plays a role in epithelial outgrowth, such as that which occurs during the development of hair follicles and limb buds. Loss of function of the related gene in humans results in ectodermal dysplasia, ectrodactyly, and macular dystrophy and congential hypotrichosis with juvenile macular dystrophy. This gene is located in the vicinity of similar cadherin genes on chromosome 8. The proprotein is further cleaved into a functional chain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Cdh3 Products(2)

mRNA Protein Name
NM_001037809.5 NP_001032898.1 cadherin-3 isoform a preproprotein
NM_007665.3 NP_031691.1 cadherin-3 isoform b preproprotein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
15148305 MGI
Cellular Component GO Annotation Evidence Reference Source
located in adherens junction IDA
IDA: Inferred from direct assay
15728677 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12060406 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cadherin-3

RPE-specific cadherin

placental cadherin

Recombinant Cdh3 Proteins

Cat. No. Product Name Accession Purity
HY-P7701 Cadherin-3 Protein, Mouse (HEK293, Fc) P10287 (E100-G647) ≥95%
HY-P700690 Cadherin-3 Protein, Mouse (HEK293, His) P10287 (E100-G647) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02336 CDH3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdh3 NCBI NCBI:1001
Macaca fascicularis Cdh3 NCBI NCBI:102142204
Susscrofa domestica Cdh3 NCBI