2. Gene
  3. Cdh6 - cadherin 6 Gene

Cdh6 - cadherin 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as cad6

Gene ID: 12563 | Gene type: protein coding

About Cdh6

Summary

This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein exhibit delay in mesenchyme-to-epithelial conversion and a loss of nephrons. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 15. [provided by RefSeq, Oct 2015]

Cdh6 Products(1)

mRNA Protein Name
NM_007666.4 NP_031692.2 cadherin-6 preproprotein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
23117660 MGI
involved in synaptic membrane adhesion IDA
IDA: Inferred from direct assay
28957665 MGI
involved in synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
28957665 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28957665 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28957665 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12139922 MGI
is active in synapse IDA
IDA: Inferred from direct assay
28957665 MGI
is active in synapse IMP
IMP: Inferred from mutant phenotype
28957665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cadherin-6

K-cadherin

kidney cadherin

Recombinant Cdh6 Proteins

Cat. No. Product Name Accession Purity
HY-P77037 Cadherin-6/KCAD Protein, Mouse (HEK293, His) P97326 (T19-A615) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-164734 Raludotatug Deruxtecan / Unkown
HY-RS02339 CDH6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdh6 NCBI NCBI:1004
Macaca fascicularis Cdh6 NCBI
Rattus norvegicus Cdh6 NCBI NCBI:25409