CNN3 - calponin 3 Gene

Homo sapiens

Gene ID: 1266 | Gene type: protein coding

About CNN3

Cytogenetic location: 1p21.3 Genomic coordinates (GRCh38): 1:94,896,957-94,927,110 (from NCBI)

This gene has 7 transcripts (splice variants), 348 orthologues and 5 paralogues. Ubiquitous expression in adrenal (RPKM 52.9), placenta (RPKM 49.2) and 24 other tissues.

Summary

This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the Cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]

CNN3 Products(3)

mRNA	Protein	Name
NM_001286055.2	NP_001272984.1	calponin-3 isoform 2
NM_001286056.2	NP_001272985.1	calponin-3 isoform 3
NM_001839.5	NP_001830.1	calponin-3 isoform 1

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in epithelial cell differentiation	IEP IEP: Inferred from expression pattern	21492153	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNN3 Protein Structure

Calponin

0
100
200
300
329 a.a.

Protein Preferred Names

Protein Names

calponin-3

calponin 3, acidic

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02894	CNN3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CNN3	VGNC	VGNC:61022
Canis familiaris	CNN3	VGNC	VGNC:39405
Rattus norvegicus	CNN3	RGD	RGD:71044
Mus musculus	CNN3	MGD	MGI:1919244
Macaca mulatta	CNN3	VGNC	VGNC:71278

Name
Email *

	Sorry, but the email address you supplied was invalid.