SLC44A3 - solute carrier family 44 member 3 Gene

Homo sapiens

Also known as CTL3

Gene ID: 126969 | Gene type: protein coding

About SLC44A3

This gene has 10 transcripts (splice variants), 154 orthologues and 4 paralogues. Broad expression in kidney (RPKM 8.6), colon (RPKM 8.5) and 20 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC44A3 Products(8)

mRNA	Protein	Name
NM_001114106.3	NP_001107578.1	choline transporter-like protein 3 isoform 1
NM_001258340.2	NP_001245269.1	choline transporter-like protein 3 isoform 3
NM_001258341.2	NP_001245270.1	choline transporter-like protein 3 isoform 4
NM_001258342.2	NP_001245271.1	choline transporter-like protein 3 isoform 5
NM_001258343.2	NP_001245272.1	choline transporter-like protein 3 isoform 6
NM_001301079.2	NP_001288008.1	choline transporter-like protein 3 isoform 7
NM_001350223.1	NP_001337152.1	choline transporter-like protein 3 isoform 8
NM_152369.5	NP_689582.2	choline transporter-like protein 3 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC44A3 Protein Structure

Choline_transpo

0
100
200
300
400
500
600
653 a.a.

Protein Preferred Names

Protein Names

choline transporter-like protein 3

SLC44A3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SLC44A3	Q8N4M1	FHL3	Homo sapiens	Q13643	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Cystinuria

CSNU	Cystinuria Type B
Cystinuria Type A	Cystinuria, Type I, Formerly
Csnu1, Formerly	Cystinuria, Type Ii, Formerly
Cystinuria, Type Iii, Formerly	Csnu3, Formerly
Cystinuria, Type Non-I, Formerly	Cystinuria-Lysinuria
Cystinuria-Lysinuria Syndrome	Csnu1
Csnu3	Cystinuria 1
Cystinuria Type A/B	Cystinuria Type I
Cystinuria Type Ii	Cystinuria Type Iii
Cystinuria Type Non-I	Cystinuria, Type A/B
Cystinuria Type 1	Cystinuria - Lysinuria
Csnu - [Cystinuria]	Cystine Disease

Iminoglycinuria

Iminoglycinuria, Digenic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13253	SLC44A3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SLC44A3	VGNC	VGNC:46419
Felis catus	SLC44A3	VGNC	VGNC:65373
Rattus norvegicus	SLC44A3	RGD	RGD:1305808
Bos taurus	SLC44A3	VGNC	VGNC:34877
Macaca mulatta	SLC44A3	VGNC	VGNC:77582
Mus musculus	SLC44A3	MGD	MGI:2384860

Name
Email *

	Sorry, but the email address you supplied was invalid.