2. Gene
  3. Cntn1 - contactin 1 Gene

Cntn1 - contactin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as usl; CNTN; F3cam

Gene ID: 12805 | Gene type: protein coding

About Cntn1

Summary

Enables carbohydrate binding activity. Involved in central nervous system myelin formation and locomotory behavior. Acts upstream of or within several processes, including nervous system development; positive regulation of neuron projection development; and positive regulation of sodium ion transport. Is anchored component of postsynaptic membrane. Is anchored component of presynaptic membrane. Is expressed in several structures, including alimentary system; brain; cranial ganglion; genitourinary system; and sensory organ. Used to study Compton-North congenital myopathy. Human ortholog(s) of this gene implicated in Compton-North congenital myopathy. Orthologous to human CNTN1 (contactin 1). [provided by Alliance of Genome Resources, Apr 2022]

Cntn1 Products(5)

mRNA Protein Name
NM_001159647.2 NP_001153119.1 contactin-1 precursor
NM_001159648.2 NP_001153120.1 contactin-1 precursor
NM_001358051.2 NP_001344980.1 contactin-1 precursor
NM_001411171.1 NP_001398100.1 contactin-1 precursor
NM_007727.3 NP_031753.1 contactin-1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables carbohydrate binding IDA
IDA: Inferred from direct assay
19458237 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12700241 MGI
Biological Process GO Annotation Evidence Reference Source
involved in central nervous system myelin formation IGI
IGI: Inferred from genetic interaction
31641127 MGI
acts upstream of or within cerebellum development IMP
IMP: Inferred from mutant phenotype
18354028 MGI
acts upstream of gene expression IMP
IMP: Inferred from mutant phenotype
16029194 MGI
involved in locomotory behavior IMP
IMP: Inferred from mutant phenotype
31641127 MGI
involved in myelination IGI
IGI: Inferred from genetic interaction
31641127 MGI
involved in myelination IMP
IMP: Inferred from mutant phenotype
31641127 MGI
acts upstream of or within neuron projection development IGI
IGI: Inferred from genetic interaction
19458237 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
16029194 MGI
acts upstream of or within positive regulation of neuron projection development IGI
IGI: Inferred from genetic interaction
18354028 MGI
acts upstream of or within positive regulation of sodium ion transport IMP
IMP: Inferred from mutant phenotype
16029194 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
1729438 MGI
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
1729438 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31171447 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

contactin-1

neural cell surface protein F3

Recombinant Cntn1 Proteins

Cat. No. Product Name Accession Purity
HY-P74224 Contactin-1/CNTN1 Protein, Mouse (HEK293, His) P12960 (M1-L1000) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02926 CNTN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntn1 NCBI NCBI:1272