ZDHHC19 - zinc finger DHHC-type palmitoyltransferase 19 Gene

Homo sapiens

Also known as DHHC19

Gene ID: 131540 | Gene type: protein coding

About ZDHHC19

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:196,197,452-196,211,400 (from NCBI)

This gene has 7 transcripts (splice variants), 112 orthologues and 17 paralogues. Restricted expression toward testis (RPKM 16.0).

Summary

Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Located in Golgi membrane; endoplasmic reticulum; and perinucleolar compartment. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC19 Products(1)

mRNA	Protein	Name
NM_001039617.2	NP_001034706.1	palmitoyltransferase ZDHHC19

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA
enables protein-cysteine S-palmitoyltransferase activity	IDA IDA: Inferred from direct assay	20074548	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in peptidyl-L-cysteine S-palmitoylation	IDA IDA: Inferred from direct assay	20074548	GOA
involved in positive regulation of aggrephagy	IDA IDA: Inferred from direct assay	37802024	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in Golgi membrane	IDA IDA: Inferred from direct assay	20074548	GOA
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	16647879	GOA
located in perinucleolar compartment	IDA IDA: Inferred from direct assay	20074548	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZDHHC19 Protein Structure

DHHC

0
100
200
309 a.a.

Protein Preferred Names

Protein Names

palmitoyltransferase ZDHHC19

DHHC-19

Related Diseases

Diseases

Alias

Chikungunya

Chikungunya Fever	Arbovirus A Chikungunya Type
Chik	Chikv Infection
Ck	Chikungunya Virus Infection
Chikungunya Haemorrhagic Fever	Chikungunya Viral Disease
Chikungunya Mosquito-Borne Viral Fever

Immunodeficiency 46

Tfrc-Related Combined Immunodeficiency	IMD46
Cid Due To Tfrc Deficiency	Combined Immunodeficiency Due To Tfrc Deficiency

Chromosome 3q29 Deletion Syndrome

Chromosome 3q29 Microdeletion Syndrome	3q29 Microdeletion Syndrome
3q Subtelomere Deletion Syndrome	3q29 Recurrent Deletion
3qter Deletion	3q29 Deletion Syndrome
Monosomy 3q29	Microdeletion 3q29 Syndrome
Del(3)(Q29)	Monosomy 3qter
3q29 Deletion	Del3q29

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16018	ZDHHC19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ZDHHC19	VGNC	VGNC:67208
Bos taurus	ZDHHC19	VGNC	VGNC:37134
Canis familiaris	ZDHHC19	VGNC	VGNC:48585
Macaca mulatta	ZDHHC19	VGNC	VGNC:79272
Rattus norvegicus	ZDHHC19	RGD	RGD:1309014
Mus musculus	ZDHHC19	MGD	MGI:2682948

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