1. Gene
  2. Dlk1 - delta like non-canonical Notch ligand 1 Gene

Dlk1 - delta like non-canonical Notch ligand 1 Gene

Mus musculus

Also known as FA1; ZOG; pG2; DlkI; Peg9; SCP1; DLK-1; Ly107; pref-1

Gene ID: 13386 | Gene type: protein coding

About Dlk1

Summary

Predicted to enable calcium ion binding activity. Involved in negative regulation of fat cell differentiation and negative regulation of vascular endothelial cell proliferation. Acts upstream of or within several processes, including bone mineralization; negative regulation of Notch signaling pathway; and positive regulation of bone resorption. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; embryo mesenchyme; genitourinary system; and nervous system. Orthologous to human DLK1 (delta like non-canonical Notch ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Dlk1 Products(4)

mRNA Protein Name
NM_001190703.1 NP_001177632.1 protein delta homolog 1 isoform 2 precursor
NM_001190704.1 NP_001177633.1 protein delta homolog 1 isoform 3 precursor
NM_001190705.1 NP_001177634.1 protein delta homolog 1 isoform 4 precursor
NM_010052.5 NP_034182.2 protein delta homolog 1 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
24928897 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within bone mineralization IMP
IMP: Inferred from mutant phenotype
21308776 MGI
acts upstream of or within embryo development IDA
IDA: Inferred from direct assay
19247431 MGI
acts upstream of or within embryonic skeletal system development IDA
IDA: Inferred from direct assay
19247431 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
21308776 MGI
acts upstream of or within negative regulation of Notch signaling pathway IGI
IGI: Inferred from genetic interaction
21419176 MGI
involved in negative regulation of fat cell differentiation IDA
IDA: Inferred from direct assay
8500166 MGI
involved in negative regulation of vascular endothelial cell proliferation IDA
IDA: Inferred from direct assay
24584117 MGI
acts upstream of or within ossification IMP
IMP: Inferred from mutant phenotype
21308776 MGI
acts upstream of or within osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
21308776 MGI
acts upstream of or within positive regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
21308776 MGI
acts upstream of or within positive regulation of cytokine production IDA
IDA: Inferred from direct assay
21308776 MGI
acts upstream of or within post-embryonic development IDA
IDA: Inferred from direct assay
19247431 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
19515692 MGI
Cellular Component GO Annotation Evidence Reference Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
18988804 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein delta homolog 1

adipocyte differentiation inhibitor protein

delta-like 1 homolog

fetal antigen 1

preadipocyte factor 1

stromal cell derived protein 1

Recombinant Dlk1 Proteins

Cat. No. Product Name Accession Purity
HY-P77915 DLK-1 Protein, Mouse (HEK293, His) Q09163-1 (A24-Q305) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Dlk1 NCBI NCBI:8788
Macaca fascicularis Dlk1 NCBI NCBI:102120804