1. Gene
  2. Drd5 - dopamine receptor D5 Gene

Drd5 - dopamine receptor D5 Gene

Mus musculus

Also known as D5R; Drd-5; Drd1b; Gpcr1

Gene ID: 13492 | Gene type: protein coding

About Drd5

Chromosome 5: 38,476,710-38,479,861 forward strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 190 orthologues, 32 paralogues and is associated with 12 phenotypes.

Summary

Enables dopamine neurotransmitter receptor activity, coupled via Gs. Acts upstream of or within several processes, including learning; long-term synaptic depression; and regulation of blood pressure. Located in brush border membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and blepharospasm. Orthologous to human DRD5 (Dopamine Receptor D5). [provided by Alliance of Genome Resources, Apr 2022]

Drd5 Products(1)

mRNA Protein Name
NM_013503.4 NP_038531.1 D(1B) dopamine receptor

Drd5 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (38 - 363)

7tm_GPCRs

7tm_GPCRs: cd14964 (40 - 64)

7tm_GPCRs

7tm_GPCRs: cd14964 (74 - 96)

7tm_GPCRs

7tm_GPCRs: cd14964 (111 - 133)

7tm_GPCRs

7tm_GPCRs: cd14964 (156 - 172)

7tm_GPCRs

7tm_GPCRs: cd14964 (216 - 239)

7tm_GPCRs

7tm_GPCRs: cd14964 (288 - 310)

7tm_GPCRs

7tm_GPCRs: cd14964 (332 - 357)

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  • 478 a.a.
Protein Preferred Names Protein Names

D(1B) dopamine receptor

d(5) dopamine receptor

dopamine D5 receptor

dopamine receptor 5

Orthologs Information

Species Symbol Source ID
Homo sapiens Drd5 NCBI NCBI:1816