2. Gene
  3. TRIM40 - tripartite motif containing 40 Gene

TRIM40 - tripartite motif containing 40 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RNF35

Gene ID: 135644 | Gene type: protein coding

About TRIM40

Cytogenetic location: 6p22.1 Genomic coordinates (GRCh38): 6:30,136,140-30,148,735 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 76 orthologues and 80 paralogues. Biased expression in small intestine (RPKM 3.6), duodenum (RPKM 3.4) and 4 other tissues.

Summary

This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]

TRIM40 Products(2)

mRNA Protein Name
NM_001286633.2 NP_001273562.1 E3 ubiquitin ligase TRIM40 isoform a
NM_138700.4 NP_619645.1 E3 ubiquitin ligase TRIM40 isoform b

TRIM40 Protein Structure

zf-C3HC4_2

zf-C3HC4_2: Zinc finger, C3HC4 type (RING finger) (14 - 56)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin ligase TRIM40

RING finger protein 35

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15045 TRIM40 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TRIM40 RGD RGD:1359645
Bos taurus TRIM40 VGNC VGNC:54243
Mus musculus TRIM40 MGD MGI:2684881