2. Gene
  3. Edar - ectodysplasin-A receptor Gene

Edar - ectodysplasin-A receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as dl; ED3; ED5; ED1R; EDA3; EDA-A1R

Gene ID: 13608 | Gene type: protein coding

About Edar

Summary

Predicted to enable transmembrane signaling receptor activity. Acts upstream of or within several processes, including animal organ development; positive regulation of NIK/NF-kappaB signaling; and positive regulation of gene expression. Located in apical part of cell and plasma membrane. Is expressed in several structures, including embryo ectoderm; integumental system; male accessory gland; oral region epithelium; and tooth. Used to study hypohidrotic ectodermal dysplasia. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Orthologous to human EDAR (ectodysplasin A receptor). [provided by Alliance of Genome Resources, Apr 2022]

Edar Products(1)

mRNA Protein Name
NM_010100.3 NP_034230.1 tumor necrosis factor receptor superfamily member EDAR precursor
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member EDAR

anhidrotic ectodysplasin receptor 1

downless

ectodermal dysplasia receptor

Recombinant Edar Proteins

Cat. No. Product Name Accession Purity
HY-P70115 EDAR Protein, Mouse (HEK293, Fc) Q9R187 (E27-I189) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04153 EDAR Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Edar NCBI NCBI:10913
Macaca fascicularis Edar NCBI NCBI:102120238
Rattus norvegicus Edar NCBI NCBI:365581